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Related Experiment Video

Updated: Jul 8, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
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Published on: April 3, 2016

Interocular axial length difference and age-related cataract.

Madhavan S Rajan1, Catey Bunce, Stephen Tuft

  • 1Moorfields Eye Hospital, London, United Kingdom. msrajan@tiscali.co.uk

Journal of Cataract and Refractive Surgery
|January 1, 2008
PubMed
Summary

Longer eyes in cataract patients show increased asymmetry and anisometropia after surgery. This axial length difference impacts refractive predictability, especially in eyes over 28mm.

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Area of Science:

  • Ophthalmology
  • Biometry
  • Cataract Surgery

Background:

  • Age-related cataract surgery aims for precise refractive outcomes.
  • Axial length is a key biometric parameter influencing refractive prediction.

Purpose of the Study:

  • To evaluate interocular differences in axial length (AL) in relation to increasing AL.
  • To assess the impact of AL on postoperative refractive predictability.
  • To analyze the magnitude of postoperative anisometropia in relation to AL.

Main Methods:

  • Retrospective analysis of 1537 patients undergoing bilateral phacoemulsification.
  • Comparison of interocular AL differences and anisometropia across AL groups (1.0 mm increments).
  • Assessment of biometry prediction error in relation to AL.

Main Results:

  • Axial length asymmetry increased with longer AL (P<.001).
  • Postoperative anisometropia increased with AL (P = .003), with higher median values for AL ≥ 28.0 mm.
  • Biometry prediction error increased with AL in left eyes (P = .006).

Conclusions:

  • Increased axial length is associated with greater interocular asymmetry and anisometropia.
  • Eyes with AL > 28.0 mm showed significantly more asymmetry and anisometropia.
  • Axial length impacts refractive predictability in cataract surgery.