Related Experiment Video
Updated: Jul 8, 2026
07:08
A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
Published on: June 6, 2025
[Selection of the living donor]
1Service de néphrologie et d'immunologie clinique, CHU de Nantes, 44093 Nantes cedex, France. maryvonne.hourmant@chu-nantes.fr
Nephrologie & Therapeutique
|January 1, 2008
Summary
Living donor selection criteria, though not fully standardized, include absence of hypertension, cardiovascular disease, and specific GFR, proteinuria, and hematuria levels. Further refinement of these guidelines is necessary for optimal donor selection.
Area of Science:
- Nephrology
- Transplantation Medicine
Context:
- Living donor selection criteria are evolving.
- Consensus recommendations were established in 2004.
- Standardization of donor evaluation is ongoing.
Purpose:
- To outline current living donor selection criteria.
- To identify key health parameters for potential kidney donors.
- To highlight areas needing further refinement in donor assessment.
Summary:
- Key criteria include absence of hypertension, cardiovascular disease, adequate Glomerular Filtration Rate (GFR) >80ml/min, limited proteinuria (<0.30g/day), and absence of renal hematuria.
- Caution is advised for donors with diabetes risk factors, BMI >30, or a history of recurrent kidney stones.
- Past cancer history is not an absolute contraindication if treatable, in remission, and non-transferable.
Impact:
- Aims to improve the safety and efficacy of living donor transplantation.
- Provides a framework for evaluating potential living kidney donors.
- Highlights the need for continued research to optimize donor selection protocols.
More Related Videos
Related Concept Videos
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
01:22Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
01:24Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...