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Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
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Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
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Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
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Updated: Jul 8, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Prescribing errors in a pediatric emergency department.

Michael L Rinke1, Margaret Moon, John S Clark

  • 1Department of Pediatrics, Johns Hopkins Hospital, Baltimore, MD, USA.

Pediatric Emergency Care
|January 1, 2008
PubMed
Summary

Prescribing errors are frequent in pediatric emergency departments for both inpatient orders and outpatient prescriptions. Interventions should focus on improving medication safety for less experienced prescribers and reinforcing safe writing practices.

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Area of Science:

  • Pediatric Emergency Medicine
  • Pharmacology
  • Patient Safety

Background:

  • Medication errors pose a significant risk in pediatric care.
  • Accurate prescribing is crucial for effective treatment in pediatric emergency settings.

Purpose of the Study:

  • To determine the frequency, prescriber, and type of prescribing errors.
  • To analyze errors in written in-house orders and ambulatory prescriptions within a pediatric emergency department (PED).

Main Methods:

  • Retrospective chart review of in-house orders (17 days) and ambulatory prescriptions (6 months).
  • Analysis focused on weight-based dosing, route, frequency, dose accuracy, and drug allergies.
  • Excluded narcotics from ambulatory prescription analysis.

Main Results:

  • 12.5% of in-house orders and 19.4% of ambulatory charts had errors.
  • Common errors included incorrect dose (4.3%) and incorrect writing (10.8%).
  • Postgraduate residents and attending physicians showed varying error rates depending on order type.

Conclusions:

  • Prescribing errors are prevalent in pediatric emergency departments.
  • Targeting interventions toward less experienced prescribers and reinforcing safe medication writing techniques is recommended.
  • Improving medication safety in PEDs requires focused interventions.