Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Comparison Tests

Comparison Tests

An infinite series composed of positive terms may either approach a finite value or increase without bound. Determining which outcome occurs is a central task in calculus, and comparison tests provide structured methods for making this determination. Rather than evaluating a series directly, these tests relate it to another series whose behavior is already known, allowing conclusions to be drawn through logical comparison.The direct comparison test applies to series with positive terms. If each...

Multiple Comparison Tests

Multiple Comparison Tests

Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...

Compacting Factor test

Compacting Factor test

The compacting factor test is a method used to assess the workability of concrete. It is especially suitable for concrete mixes containing aggregates up to one and a half inches in size. This test involves specialized equipment consisting of two truncated cone-shaped hoppers and a cylinder, all with polished interior surfaces to minimize friction.
The procedure begins by placing concrete into the upper hopper without any compaction. Once filled, the bottom door of this hopper is opened,...

Problem-Solving: Tuning of a Guitar String

Problem-Solving: Tuning of a Guitar String

In the case of stringed instruments like the guitar, the elastic property that determines the speed of the sound produced is its linear mass density or the mass per unit length. This is simply called the linear density. If the string's linear density is constant along the string, then the linear density is simply the total mass divided by the total length.
The string's wave speed can be regulated by varying the linear density. Tension is the other property that determines the speed of...

DNA Topoisomerases

DNA Topoisomerases

Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types. Type I...

Lattice Centering and Coordination Number

Lattice Centering and Coordination Number

The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Super-Resolution Confocal Microscopy Enabled by Fluorescence Intensity Ratio Encoding and Difference.

Nano letters·2025

Same author

Ketogenic diet and β-hydroxybutyrate inhibit HDAC1 to preserve vascular smooth muscle cell function in thoracic aortic aneurysm.

Journal of advanced research·2025

Same author

Nanoscale island manipulation and construction of heterojunctions by mechanical collision of 2D materials.

Physical chemistry chemical physics : PCCP·2025

Same author

Dumbbell-Shaped Gold Nanorod@Mesoporous Palladium Nanozymes for NIR-II-Triggered Photocatalytic Amplification and Trimodal Cancer Therapy.

ACS applied materials & interfaces·2025

Same author

Corrigendum to "Discovery of new 1,2,3,4-tetrahydro-β-carboline derivatives decorated with 3-N-substituted propionyl moiety flexibly bridged-chain as reactive oxygen species inducer for efficient antibacterial treatment" [Bioorganic Chemistry 160 (2025) 108473].

Bioorganic chemistry·2025

Same author

Elucidation of novel turnagainolides and their biosynthetic gene cluster in <i>Bacillus subtilis</i>.

Applied and environmental microbiology·2025

Search research articles

Related Experiment Video

Updated: Jul 8, 2026

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Comparison of TOPS strings based on LZ complexity.

Liwei Liu¹, Tianming Wang

¹Department of Applied Mathematics, Dalian University of Technology, Dalian 116024, PR China. daliguowei@163.com

Journal of Theoretical Biology

|January 2, 2008

Summary

This summary is machine-generated.

This study introduces a new method for comparing protein structures using Topology of Protein Structure (TOPS) cartoons. The LZ algorithm efficiently compares these simplified protein representations, aiding in functional and evolutionary analysis.

Related Experiment Videos

Last Updated: Jul 8, 2026

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

Area of Science:

Structural bioinformatics
Computational biology
Protein science

Background:

Protein structure comparison is crucial for understanding protein function and evolution.
Topology of Protein Structure (TOPS) cartoons offer a simplified 2D representation of protein topology.
Coarse-grained descriptions are valuable for large-scale structural analysis.

Purpose of the Study:

To develop and evaluate a novel method for comparing protein structures.
To leverage the LZ algorithm for efficient comparison of TOPS strings.
To enhance the analysis of protein functions and evolutionary relationships through structural comparison.

Main Methods:

Generation of Topology of Protein Structure (TOPS) cartoons.
Application of the LZ (Lempel-Ziv) algorithm for string comparison.
Comparative analysis of TOPS string representations.

Main Results:

The LZ algorithm provides an effective means to compare TOPS strings.
Demonstrated the feasibility of using simplified topological representations for structural comparison.
The method facilitates the study of protein structural similarities.

Conclusions:

Comparing TOPS strings with the LZ algorithm is a viable approach for protein structure analysis.
This method can contribute to a deeper understanding of protein function and evolutionary pathways.
Simplified structural representations offer computational advantages for large datasets.