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Updated: Jul 8, 2026

A Rat Dry Eye Model with Lacrimal Gland Dysfunction Induced by Scopolamine
Published on: February 9, 2024
Control of drooling using transdermal scopolamine skin patches. A case report
Abigail Mato Montero1, Jacobo Limeres Posse, Inmaculada Tomás Carmona
1Departamento de Estomatología, Unidad de Pacientes Especiales, Facultad de Medicina y Odontología, Universidad de Santiago de Compostela, Spain.
Abstract:
Transdermal scopolamine has been shown to be very useful in the management of drooling, particularly in patients with neurological or neuropsychiatric disturbances or severe developmental disorders. In this paper, we present the case of a 24-year-old patient with a diagnosis of cerebral palsy and a severe problem of drooling, exacerbated by marked mandibular prognathism. After exclusion of other therapeutic alternatives, it was decided to use sustained-release transdermal scopolamine patches (Scopoderm TTS). This technique consists of the application every three days of a patch with 1.5 mg of scopolamine in the area of the mastoid apophysis; the patch releases a dose of 0.5 mg of the active substance over each 24 hour period. The patient underwent periodic clinical and laboratory follow-up over a period of three years, achieving satisfactory results with no significant undesirable effects.
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