Related Experiment Video
Updated: Jul 8, 2026

Prediction of HIV-1 Coreceptor Usage (Tropism) by Sequence Analysis using a Genotypic Approach
Published on: December 1, 2011
[Clinical spectrum of HIV infection and classification systems]
Abstract:
Diseases spectrum caused by the human immunodeficiency virus (HIV) manifests with a wide range of clinical symptoms, due to the involvement of different organs and systems. Patients infected with HIV may present with a spectrum of clinical manifestations ranging from asymptomatic infection to severe immunodeficiency associated with different secondary infections, tumors, or other conditions. Since 1981 when the acquired immunodeficiency syndrome (AIDS) was recognized and the causative agent discovered thereafter, various systems have been proposed to classify manifestations of HIV infection and AIDS definition has bean revised several times. The evolution of classification systems for HIV infection and revision of case definitions for AIDS have closely followed current knowledge of biologic features of this infection, primarily related to its natural hystory and predictive value of immunologic parametres. Various classification systems for HIV infection, which have been widely used in clinical practice will be discussed in this review.
Related Concept Videos
Sexually Transmitted Infections
Retrovirus Life Cycles
Microbial Classification System
Cryptococcal Meningitis
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Infectious Diseases and Their Occurrence
