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Fast-responding automated airway temperature probe.

A L Clary¹, J M Fouke

¹Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106.

Medical & Biological Engineering & Computing

|September 1, 1991

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Asthmatic patients exhibit rapid airway temperature changes after exercise. A new device accurately monitors these thermal events, potentially revealing insights into airway instability in asthma.

Area of Science:

Respiratory physiology
Biomedical engineering
Medical instrumentation

Background:

Asthma is characterized by airway instability.
Rapid thermal changes occur in asthmatic airways post-hyperpnea.
These thermal events may correlate with abnormal airway wall blood flow.

Purpose of the Study:

To develop a novel device for monitoring airway thermal transients in asthmatic subjects.
To investigate the relationship between airway temperature changes and asthma pathophysiology.

Main Methods:

Development of fast-responding thermistors and associated electronics.
Utilizing a small-mass temperature sensor and IBM-AT compatible computer for rapid system response.
Calibration and safety testing according to American Hospital Association standards.

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Main Results:

The developed apparatus achieves a system response time an order of magnitude greater than previous devices.
The device is stable, reproducible, easily calibrated, and shows no hysteresis within the 15-35°C range.
The system meets all electrical safety standards.

Conclusions:

The new device effectively monitors rapid thermal transients in asthmatic airways.
This technology can aid in understanding airway wall blood flow abnormalities and geometry instability in asthma.
Further research can explore the clinical implications of these thermal events in asthma management.