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Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research

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[A case of cat scratch disease].

Cafer Eroğlu¹, Nihat Candir, Adem Dervişoğlu

¹Ondokuz Mayis Universitesi Tip FakOltesi, Klinik Mikrobiyoloji ve Infeksiyon Hastaliklan Anabilim Dali, Samsun. ceroglu@omu.edu.tr

Mikrobiyoloji Bulteni

|January 5, 2008

Summary

Cat scratch disease (CSD), caused by Bartonella henselae, is typically seen in younger individuals. This case highlights CSD diagnosis in a 30-year-old adult presenting with lymphadenopathy after cat contact, successfully treated with azithromycin.

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Area of Science:

Infectious Diseases
Bacteriology
Clinical Case Study

Background:

Cat scratch disease (CSD) is an infection caused by Bartonella henselae, commonly affecting children and young adults.
It typically presents with self-limiting lymphadenopathy.

Observation:

A 30-year-old male presented with lymphadenopathy, negative inflammatory markers, and unremarkable initial infectious workup.
Bartonella henselae was not detected via blood or lymph node cultures, nor PCR, potentially due to prior antibiotic treatment.
Diagnosis was established based on cat contact history, clinical presentation, and necrotizing granulomatous inflammation on lymph node biopsy.

Findings:

The patient experienced complete resolution of lymphadenopathy after a five-day course of oral azithromycin.
Despite negative microbiological and PCR results, clinical and histopathological findings confirmed CSD.

Implications:

CSD should be considered in adult patients with unexplained lymphadenopathy and a history of cat exposure.
This case underscores the importance of clinical suspicion and patient history in diagnosing CSD, especially in adults where it is less common.