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Updated: Jul 8, 2026

Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights

Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights

Published on: October 13, 2023

Nodular scleritis and Sweet's syndrome.

Melissa Hsing Yi Wong¹, Daniel Hsien Wen Su, Raymond Ser Keat Loh

¹Department of Ophthalmology, Changi General Hospital, Singapore, Singapore.

Clinical & Experimental Ophthalmology

|January 5, 2008

Summary

This case study highlights nodular scleritis as an ocular manifestation of Sweet's syndrome. Prompt diagnosis and treatment of this eye condition are crucial for preventing vision loss.

Area of Science:

Ophthalmology
Dermatology
Rheumatology

Background:

Sweet's syndrome is an uncommon neutrophilic dermatosis.
Ocular manifestations, though rare, can occur in Sweet's syndrome.

Observation:

A 40-year-old woman with a history of Sweet's syndrome presented with acute red, painful, and blurred vision in her right eye.
Clinical examination revealed nodular scleritis, confirmed as secondary to Sweet's syndrome after excluding other systemic causes.

Findings:

The patient responded well to systemic corticosteroids, achieving complete resolution of scleritis.
Recurrence of skin inflammation upon corticosteroid tapering necessitated the addition of colchicine and dapsone for dermatologic management.

Implications:

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Nodular scleritis can be a presenting or associated ocular feature of Sweet's syndrome.
Early diagnosis and appropriate management of ocular involvement in Sweet's syndrome are vital to prevent long-term visual morbidity.
Multidisciplinary management involving ophthalmology, dermatology, and rheumatology may be required for complex cases.