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Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
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PRALINETM: a strategy for improved multiple alignment of transmembrane proteins

Walter Pirovano1, K Anton Feenstra, Jaap Heringa

  • 1Centre for Integrative Bioinformatics VU (IBIVU), VU University Amsterdam, De Boelelaan 1081A, 1081 HV Amsterdam, The Netherlands.

Bioinformatics (Oxford, England)
|January 5, 2008
PubMed
Summary

PRALINETM enhances multiple sequence alignment for transmembrane proteins by integrating membrane-specific features. This new method significantly improves alignment quality compared to standard techniques.

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