Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A note on difficult structure alignment problems.

Manfred J Sippl1, Markus Wiederstein

  • 1Center of Applied Molecular Engineering, Division of Bioinformatics, Department of Molecular Biology, University of Salzburg, Hellbrunnerstr. 34, 5020 Salzburg, Austria. sippl@came.sbg.ac.at

Bioinformatics (Oxford, England)
|January 5, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Self-assembling proteins compose the chemically resistant shell biomaterial of planktonic tintinnid ciliates.

Nature communications·2026
Same author

Metabolic disease variants rewire gene regulation through disruption of DNA G-quadruplex structures.

Genome biology·2026
Same author

Iron-Dependent allergenicity of Alt a 1: A link between fungal nutritional immunity and allergic sensitization.

Mucosal immunology·2025
Same author

Cooperative Hedgehog/GLI and JAK/STAT signaling drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer.

Cell communication and signaling : CCS·2025
Same author

Mould allergen Alt a 1 spiked with the micronutrient retinoic acid reduces Th2 response and ameliorates Alternaria allergy in BALB/c mice.

Allergy·2024
Same author

Nutritional Provision of Iron Complexes by the Major Allergen Alt a 1 to Human Immune Cells Decreases Its Presentation.

International journal of molecular sciences·2023
Same journal

MCFST: Spatial domain identification method based on multi-view graph convolutional network and graph fusion network.

Bioinformatics (Oxford, England)·2026
Same journal

SpaBiT: Enhancing Spatial Transcriptomics Resolution via Bidirectional Attention Transformers.

Bioinformatics (Oxford, England)·2026
Same journal

EDEL: Enhancing Dense Retrievers for Curation of Biomedical Knowledge Bases.

Bioinformatics (Oxford, England)·2026
Same journal

Informative Relational Learning for Adverse Reaction Prediction with Enhanced Generalization to Novel Drugs.

Bioinformatics (Oxford, England)·2026
Same journal

An interpretable deep learning framework uncovers features governing CRISPR-Cas9 genome-editing efficiency.

Bioinformatics (Oxford, England)·2026
Same journal

3DICE: Interpretable 3D Cross-Modal Learning for Drug-Target Interaction Prediction and Large-Scale Drug Discovery.

Bioinformatics (Oxford, England)·2026
See all related articles

TopMatch is a web service for protein structure alignment, aiding in visualizing structural similarities and classifications. This tool is essential for advancing structural biology research.

Area of Science:

  • Structural biology
  • Computational biology
  • Bioinformatics

Background:

  • Protein structure alignment and superposition are crucial technologies in structural biology.
  • The TopMatch web service provides a public resource for these analyses.

Purpose of the Study:

  • To introduce and demonstrate the utility of the TopMatch web service.
  • To showcase its application in visualizing structural similarities and protein classifications.

Main Methods:

  • Utilizing the TopMatch web service for computational protein structure alignment.
  • Applying the tool for visualization of structural relationships.

Main Results:

  • TopMatch effectively aligns protein structures, revealing similarities.

Related Experiment Videos

  • The service aids in understanding relationships within protein classifications through visualization.

    • Conclusions:

    • The TopMatch web service is an indispensable tool for structural biology.
    • Its application facilitates the analysis and interpretation of protein structural data.