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Ureaplasma urealyticum meningitis in an adult patient
Walter Geissdörfer1, Günter Sandner, Stefan John
1Institute of Clinical Microbiology, Immunology and Hygiene, University of Erlangen, Erlangen, Germany.
Journal of Clinical Microbiology
|January 5, 2008
Abstract:
A 38-year-old patient developed meningitis after a complicated kidney transplantation and organ rejection. Ureaplasma urealyticum was identified as the etiological agent by molecular and microbiological analyses of the cerebrospinal fluid. The patient was successfully treated with doxycycline and chloramphenicol. This is the first report of Ureaplasma urealyticum meningitis in an adult.
Insights
A rare case of adult Ureaplasma urealyticum meningitis occurred post-kidney transplant. Prompt treatment with doxycycline and chloramphenicol led to successful recovery, marking the first reported instance in an adult.
Area of Science:
- Infectious Diseases
- Nephrology
- Microbiology
Background:
- Kidney transplantation is a complex procedure with potential complications.
- Organ rejection can necessitate immunosuppressive therapy, increasing infection risk.
Observation:
- A 38-year-old patient experienced meningitis following a complicated kidney transplant and organ rejection.
- Cerebrospinal fluid analysis revealed Ureaplasma urealyticum as the causative pathogen.
Findings:
- Molecular and microbiological techniques confirmed Ureaplasma urealyticum meningitis.
- The patient achieved a full recovery after treatment with doxycycline and chloramphenicol.
Implications:
- This case highlights Ureaplasma urealyticum as a potential cause of meningitis in immunocompromised adults.
- It underscores the importance of considering atypical pathogens in post-transplant meningitis.
- Successful treatment with specific antibiotics offers a therapeutic precedent.
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