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Growth velocity predicts recurrence of sleep-disordered breathing 1 year after adenotonsillectomy
Raouf Amin1, Leonard Anthony, Virend Somers
1Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. raouf.amin@cchmc.org
Insights
Rapid weight gain, obesity, and being African American increase the risk of sleep-disordered breathing (SDB) recurrence after adenotonsillectomy in children. Monitoring BMI gain velocity is crucial for identifying at-risk individuals.
Area of Science:
- Pediatric Surgery
- Sleep Medicine
- Cardiovascular Health
Background:
- Adenotonsillectomy is the primary treatment for pediatric sleep-disordered breathing (SDB).
- Predictors for SDB recurrence post-surgery and associated cardiovascular risks remain unclear.
Purpose of the Study:
- To determine if increased body mass index (BMI) velocity (change in BMI per year) independently predicts SDB recurrence one year after adenotonsillectomy.
Main Methods:
- Prospective follow-up of children with SDB and hypertrophy of tonsils, alongside a healthy control group, for one year.
- Serial polysomnographies, BMI, and blood pressure measurements were taken pre- and post-operatively at multiple time points.
Main Results:
- Gain velocity in BMI, overall BMI, and African American ethnicity were significant predictors of SDB recurrence.
- Children experiencing SDB recurrence had higher systolic blood pressure at one year compared to baseline and controls.
Conclusions:
- Rapid BMI gain, obesity, and African American ethnicity are independent risk factors for SDB recurrence after adenotonsillectomy.
- Long-term monitoring of BMI gain velocity in children with SDB is essential for identifying those at risk for recurrence and potential hypertension.
Rationale:
Adenotonsillectomy, the first line of treatment of sleep-disordered breathing (SDB), is the most commonly performed pediatric surgery. Predictors of the recurrence of SDB after adenotonsillectomy and its impact on cardiovascular risk factors have not been identified.
Objectives:
Demonstrate that gain velocity in body mass index (BMI) defined as unit increase in BMI/year confers an independent risk for the recurrence of SDB 1 year after adenotonsillectomy.
Methods:
Children with SDB and hypertrophy of the tonsils and a comparison group of healthy children were followed prospectively for 1 year.
Measurements And Main Results:
Serial polysomnographies, BMI, and blood pressure were obtained before adenotonsillectomy and 6 weeks, 6 months, and 1 year postoperatively. Gain velocity in BMI, BMI and being African American (odds ratios, 4-6/unit change/yr; 1.4/unit and 15, respectively) provided equal amounts of predictive power to the risk of recurrence of SDB. In the group that experienced recurrence, systolic blood pressure at 1 year was higher than at baseline and higher than in children who did not experience recurrence.
Conclusions:
Three clinical parameters confer independent increased risk for high recurrence of SDB after adenotonsillectomy: gain velocity in BMI, obesity, and being African American. A long-term follow-up of children with SDB and monitoring of gain velocity in BMI are essential to identifying children at risk for recurrence of SDB and in turn at risk for hypertension.
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