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Published on: August 1, 2025
Coarctation of aorta in a 52-year-old female
Mouhammed Joumaa1, David Graham, Howard Rosman
1St. John Hospital and Medical Center, 22101 Moross, Detroit, MI, 48236, USA. mouhammed.joumaa@stjohn.org
Insights
Coarctation of the aorta, a congenital heart defect, can be diagnosed late in life. This case highlights a 52-year-old woman with aortic coarctation and bicuspid aortic valve presenting with symptoms in her fifth decade.
Area of Science:
- Cardiology
- Vascular Surgery
- Congenital Heart Disease
Background:
- Coarctation of the aorta is a congenital cardiovascular malformation affecting 5-10% of patients with such conditions.
- It typically originates distal to the left subclavian artery and is associated with significant morbidity and mortality risks.
- Diagnosis often relies on symptoms and physical findings, especially in early life, though many remain asymptomatic until adulthood.
Observation:
- This case report details a 52-year-old female with a late diagnosis of aortic coarctation.
- The patient presented with chest discomfort, fatigue, and dyspnea in her fifth decade of life.
- She also had an undiagnosed bicuspid aortic valve, a common co-occurring anomaly.
Findings:
- The patient was relatively asymptomatic until her fifth decade, indicating a potentially subtle presentation of aortic coarctation.
- Clinical presentation and a markedly elevated gradient were key diagnostic indicators.
- The combination of aortic coarctation and bicuspid aortic valve was identified in this adult patient.
Implications:
- Late diagnosis of aortic coarctation is possible, emphasizing the need for vigilance in adult cardiovascular assessments.
- Bicuspid aortic valve may coexist with aortic coarctation, influencing clinical presentation and management.
- Prompt diagnosis and referral for corrective therapy are crucial for managing symptomatic adult patients with aortic coarctation.
Abstract:
Coarctation of the aorta is a complex vascular lesion that usually originates distal to the left subclavian artery. It accounts for 5-10% of all congenital cardiovascular malformations and carries a high morbidity and mortality risk. Symptoms depend on the severity of the disease and other coexisting anomalies. Early in life, diagnosis is usually based on significant symptoms and physical findings. Many patients remain asymptomatic until adulthood, with most being diagnosed in the 2nd or 3rd decade. In this case report, we present a late diagnosis of aortic coarctation with a bicuspid aortic valve in a 52-year-old female. Our patient was relatively asymptomatic until she presented with chest discomfort, fatigue and dyspnea in her fifth decade of life. Based on the clinical presentation and the markedly elevated gradient, the patient was referred for corrective therapy.
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