Related Experiment Video

Updated: Jul 8, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
04:37

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension

Published on: June 6, 2025

Blood pressure control in the patient with difficult-to-control hypertension: which agent for which patient?

George L Bakris1, James R Sowers, Keith C Ferdinand

  • 1University of Chicago, IL, USA.

Preventive Cardiology
|January 5, 2008
PubMed

Insights

This expert panel focused on managing difficult-to-control hypertension. Key experts discussed strategies for patients with resistant hypertension, offering insights for clinical practice.

Area of Science:

  • Cardiology
  • Hypertension Management

Background:

  • Difficult-to-control hypertension poses significant challenges in patient care.
  • Effective management strategies are crucial for improving patient outcomes and reducing cardiovascular risk.

Purpose of the Study:

  • To convene an expert panel to discuss and provide insights on managing patients with difficult-to-control hypertension.
  • To share expert perspectives on current approaches and potential advancements in hypertension treatment.

Main Methods:

  • An expert panel discussion was convened on November 16, 2007.
  • The panel was moderated by leading hypertension specialists.
  • Discussion focused on clinical scenarios and management strategies for resistant hypertension.

Main Results:

  • The panel provided a comprehensive overview of challenges in managing resistant hypertension.
  • Expert insights were shared on pharmacological and non-pharmacological approaches.
  • Discussion highlighted the importance of individualized treatment plans.

Conclusions:

  • Effective management of difficult-to-control hypertension requires a multidisciplinary approach.
  • Adherence to treatment guidelines and personalized patient care are essential.
  • Further research and clinical strategies are needed to optimize outcomes for these patients.

Related Concept Videos

Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
Blood Pressure01:30

Blood Pressure

Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the diastolic...
Blood Pressure01:24

Blood Pressure

The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors01:30

Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors

Angiotensin-converting enzyme (ACE), a vital component of the renin-angiotensin-aldosterone system, is abundant in lung endothelial cells. ACE converts the inactive decapeptide, angiotensin I, into the active octapeptide, angiotensin II. This potent vasoconstrictor narrows blood vessels, increasing resistance to blood flow and elevating blood pressure. Angiotensin II also stimulates aldosterone production, encouraging kidney cells to reabsorb more sodium and water from urine, thereby increasing...