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Updated: Jul 8, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Posterior cranial fossa gangliogliomas
Sam Safavi-Abbasi1, Federico Di Rocco, Kraisri Chantra
1Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona.
Ganglioglioma (GG) in the cerebellum is rare and can be missed by CT scans. Magnetic resonance imaging (MRI) is crucial for diagnosing this brain tumor, which can be effectively managed with partial removal.
Area of Science:
- Neuro-oncology
- Neuropathology
- Neuroradiology
Background:
- Ganglioglioma (GG) is a rare primary central nervous system tumor, typically occurring supratentorially.
- Cerebellar GGs are exceptionally uncommon, with limited case reports in existing literature.
Observation:
- This report details the first known case of a cerebellar GG exhibiting supratentorial extension.
- The patient, a 29-year-old male, presented with an 11-year history of intermittent headaches.
- Initial cranial computerized tomography (CT) scans were negative, delaying diagnosis.
Findings:
- Magnetic resonance (MR) imaging revealed a space-occupying lesion in the right cerebellar hemisphere with superior extension.
- Pathological examination confirmed the tumor composed of atypical ganglion cells and astrocytes, consistent with cerebellar GG.
- The patient experienced significant symptom improvement following partial tumor removal.
Implications:
- Cerebellar GGs can evade CT detection, presenting with prolonged, nonspecific symptoms.
- MR imaging is vital for accurate diagnosis of infratentorial GGs.
- Partial resection of cerebellar GG can lead to favorable outcomes and symptom remission.
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