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[A case of gallbladder adenoma with wide base]
Koji Nonogaki1, Yoshiki Hirooka, Akihiro Itoh
1Department of Gastroenterology, Nagoya University Graduate School of Medicine.
Summary
A rare case of gallbladder tubular adenoma presented as a wide-based lesion. This gallbladder tumor was initially suspected as carcinoma but confirmed as benign adenoma post-surgery.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Diagnostic Imaging
Context:
- Gallbladder lesions require accurate diagnosis to differentiate benign from malignant conditions.
- Wide-based gallbladder adenomas are uncommon, posing diagnostic challenges.
- Advanced imaging modalities like endoscopic ultrasound (EUS) aid in characterizing gallbladder wall abnormalities.
Purpose:
- To report a rare case of a wide-based gallbladder adenoma.
- To discuss the diagnostic considerations and imaging findings of this rare entity.
- To highlight the importance of histopathological confirmation in gallbladder lesions.
Summary:
- A 65-year-old male presented with a gallbladder elevated lesion, initially evaluated with abdominal ultrasound (US) and endoscopic ultrasound (EUS).
- Imaging revealed a hypoechoic tumor with a wide base and irregular outer layer, leading to a preoperative diagnosis of gallbladder carcinoma.
- Post-cholecystectomy, the lesion was histopathologically confirmed as a tubular adenoma, with negative p53 immunostaining.
Impact:
- This case underscores the importance of considering benign, albeit rare, pathologies in the differential diagnosis of gallbladder tumors.
- It emphasizes the role of integrated diagnostic approaches, combining imaging and pathology, for precise gallbladder lesion characterization.
- Reporting rare cases contributes to a better understanding of gallbladder adenoma variations and their clinical presentation.
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