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Updated: Jul 8, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Long-delayed onset of chest wall pain defining a patient with SAPHO syndrome
1Division of Rheumatology, Department of Internal Medicine, American University of Beirut Medical Center, Riad Solh Cairo Street, Beirut, Lebanon.
Abstract:
A 57-year-old woman presented with 2 months history of right chest pain with direct tenderness and swelling over the right sternoclavicular joint. She had a 20-year history of skin rash over both soles and palms suggestive of pustulosis palmaris and plantaris without musculoskeletal symptoms. CT scan of the right sternoclavicular joint showed osteolysis of the joint and adjacent sclerosis. 99mTechnetium bone scan was abnormal with increased uptake over the joint and manubrium. She was diagnosed with SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis). This case report emphasizes the long duration that can lapse between onset of initial skin manifestations and musculoskeletal symptoms to define SAPHO syndrome.
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