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Related Experiment Videos

The Humphrey ADE system: evaluation in paediatric use.

C E Orlikowski1, M C Ewart, R M Bingham

  • 1Department of Anaesthesia, Hospital for Sick Children, London.

British Journal of Anaesthesia
|February 1, 1991
PubMed
Summary

The Humphrey ADE breathing system effectively supported pediatric patients during mechanical ventilation and spontaneous breathing. It performed similarly to T-piece circuits, with specific fresh gas flow recommendations for optimal use.

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Area of Science:

  • Anesthesiology
  • Pediatric Critical Care
  • Respiratory Support Devices

Background:

  • The Humphrey ADE single lever parallel form breathing system is a device used in pediatric respiratory support.
  • Evaluating its performance in mechanically ventilated and spontaneously breathing children is crucial for clinical application.

Purpose of the Study:

  • To assess the efficacy and safety of the Humphrey ADE breathing system in pediatric patients.
  • To compare its performance against established breathing circuits like the Jackson-Rees modification of Ayre's T-piece.

Main Methods:

  • The study involved 17 children requiring mechanical ventilation and 10 spontaneously breathing children.
  • Performance was evaluated in different modes: controlled ventilation (E mode) and hand ventilation (A mode).

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  • Fresh gas flow (FGF) rates and end-tidal partial pressure of carbon dioxide (PETCO2) were measured.

    • Main Results:

    • During controlled ventilation (E mode), the ADE system's performance was comparable to the T-piece circuit with standard or weight-based FGF.
    • In hand ventilation (A mode), mean PETCO2 was 5.3 kPa, and no rebreathing occurred in spontaneously breathing patients at 3 L/min FGF.
    • Rebreathing during spontaneous breathing in A mode began at 124 ml/kg/min FGF.

    Conclusions:

    • The Humphrey ADE circuit demonstrated satisfactory performance across all evaluated modes in pediatric patients.
    • For controlled ventilation (E mode), FGF adjustment should follow T-piece circuit recommendations.
    • For hand ventilation (A mode), a FGF exceeding 3 L/min is advised.