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Related Experiment Video

Updated: Jul 8, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Bacteriological study of epidermal cysts.

Shuichi Kuniyuki¹, Yuki Yoshida, Naoki Maekawa

¹Department of Dermatology, Osaka City General Hospital, Miyakojima-Hondori 2-13-22, Miyakojima-ku, Osaka, Japan. kuniyuki@ocgh.hospital.city.osaka.jp

Acta Dermato-Venereologica

|January 8, 2008

Summary

This summary is machine-generated.

Bacterial infection, particularly anaerobes, significantly contributes to inflamed epidermal cysts. This study suggests anaerobes play a key role in the inflammatory process of these skin lesions.

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Last Updated: Jul 8, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Area of Science:

Dermatology
Microbiology

Background:

Epidermal cysts are common skin lesions.
The role of bacterial infection in epidermal cyst inflammation is not fully understood.

Purpose of the Study:

To investigate the role of bacterial infection in the inflammatory process of epidermal cysts.
To compare bacterial presence in inflamed versus uninflamed epidermal cysts.

Main Methods:

Collected samples from 152 patients with epidermal cysts (115 inflamed, 37 uninflamed).
Performed aerobic and anaerobic bacterial cultures on all samples.
Analyzed bacterial isolates to identify potential pathogens.

Main Results:

Significantly higher rates of bacterial growth and anaerobe recovery were observed in inflamed epidermal cysts compared to uninflamed ones.
Anaerobic bacteria were predominant in inflamed cysts.
Distinguishing between bacterial infection and colonization in epidermal cysts remains challenging.

Conclusions:

The predominance of anaerobes in inflamed epidermal cysts strongly suggests their involvement in the inflammatory process.
Further research is needed to clarify the distinction between infection and colonization.
Findings highlight the potential role of anaerobic bacteria in epidermal cyst pathogenesis.