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Updated: Jul 8, 2026

Defining Substrate Specificities for Lipase and Phospholipase Candidates
Published on: November 23, 2016
New biological activity against phospholipase A2 by Turmerin, a protein from Curcuma longa L
Mukunda Chethankumar1, Leela Srinivas
1Adichunchanagiri Biotechnology and Cancer Research Institute, Balagangadharanatha Nagara, 571 448 Mandya, Karnataka, India.
Abstract:
Turmerin is a protein from Turmeric (Curcuma longa L.) with a relative molecular mass of 14 kDa. The protein inhibits the enzymatic activity and neutralizes the pharmacological properties, such as cytotoxicity, oedema and myotoxicity of multitoxic phospholipase A2 (NV-PLA2) of cobra (Naja naja) venom at a 1:2.5 molar ratio of NV-PLA2:Turmerin. A Lineweaver-Burk plot indicates that Turmerin follows a linear mixed type of inhibition.
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