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[Ascher's syndrome].

F Halling1, D Sandrock, H A Merten

  • 1Zentrum Zahn-, Mund-Kieferheilkunde der Universität Göttingen.

Deutsche Zeitschrift Fur Mund-, Kiefer- Und Gesichts-Chirurgie
|November 1, 1991
PubMed
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Ascher's syndrome, a rare condition, involves eyelid drooping and double lips. This case highlights its varied presentation, including associated hypothyroidism and hair loss.

Area of Science:

  • Ophthalmology
  • Endocrinology
  • Dermatology

Background:

  • Ascher's syndrome is a rare disorder characterized by the triad of blepharochalasis, double lip, and goiter.
  • The complete triad is not always present, with goiter being particularly variable.

Observation:

  • A case study of a 58-year-old patient presenting with Ascher's syndrome is detailed.
  • The patient exhibited blepharochalasis and a double upper and lower lip.
  • Associated conditions included subclinical hypothyroidism and alopecia areata totalis.

Findings:

  • This case demonstrates a less common presentation of Ascher's syndrome, lacking the typical goiter.
  • The co-occurrence of subclinical hypothyroidism and alopecia areata totalis provides further insight into potential systemic associations.

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  • Differential diagnosis for double lips is crucial, considering other etiological factors.

    • Implications:

    • This case broadens the understanding of Ascher's syndrome's clinical spectrum.
    • It underscores the importance of considering associated endocrine and dermatological conditions.
    • Further research may elucidate the complex pathophysiology and genetic underpinnings of Ascher's syndrome.