The influence of response conflict on error processing: evidence from event-related fMRI

The ability to detect errors is a crucial prerequisite for the appropriate adjustment of behavior to future situations. In the present event-related fMRI study, we provide evidence for the existence of different error-related networks within the human brain using a Simon task based on coherent motion perception. While errors related to incompatible trials were mainly associated with activation of the rostral anterior cingulate cortex (rACC) and the precuneus/posterior cingulate, errors related to trials without pre-response conflict showed specific activation in the right inferior parietal cortex. Despite this functional dissociation of brain networks, conjunction analysis revealed common clusters of activation in the medial wall (dorsal anterior cingulate cortex (dACC) and medial superior frontal cortex (msFC)), and bilateral inferior frontal gyrus/insula, consistent with earlier reports of error-related BOLD-signal increases. The present data support the view that despite of an overlapping core system of error processing, additional brain areas come into play depending on the existence or absence of cognitive conflict.