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Apoptosis in tongue squamous cell carcinoma and its correlation with clinically occult cervical metastasis
Fernando D Molina1, Eny M G Bertollo, Claudiane M Assis
1Department of Otorinolaryngology and Head & Neck Surgery Service, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University, UNESP, São José do Rio Preto, SP, Brazil.
Abstract:
Squamous cell carcinoma of the tongue is one of the most common head and neck cancer. Treatment in the early stages is still controversial. This study aims to correlate the apoptosis rate of primary tongue cancer with cervical node metastasis, found in the histopathological studies of specimens obtained from neck dissections or during clinical follow-up. Twenty patients, 65% males, mean age 64.5 years, without clinical evidence of cervical metastasis was included. Eighty-five percent were smokers and 40% were alcohol abusers. Mann-Whitney test was used for statistical analysis (p
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