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[Radiographic changes in the jaw bones of children with chronic renal failure]
1Zentrum für Zahn-, Mund- und Kieferkrankheiten der Westfalischen Wilhelms-Universität Münster.
Deutsche Zahnarztliche Zeitschrift
|November 1, 1991
Summary
Radiographic changes in children
Area of Science:
- Pediatric Nephrology
- Skeletal Radiology
- Pediatric Radiology
Background:
- Chronic renal failure (CRF) in children can lead to significant skeletal complications.
- Renal osteodystrophy is a common manifestation of CRF, affecting bone health.
- Jawbone abnormalities may serve as early indicators of skeletal disease in pediatric CRF.
Purpose of the Study:
- To investigate the prevalence and characteristics of jawbone radiographic changes in children with CRF.
- To correlate jawbone abnormalities with other skeletal radiographic findings and laboratory data.
- To assess the utility of jawbone changes for early detection of renal insufficiency in children.
Main Methods:
- Retrospective analysis of radiographic examinations in 34 children with chronic renal failure.
- Evaluation of jawbone radiographs for specific changes, including lamina durae alterations.
- Comparison of jawbone findings with radiographic abnormalities in other skeletal regions and serum levels of parathyroid hormone (iPTH-C) and alkaline phosphatase.
Main Results:
- Twenty-seven out of 34 children exhibited signs of renal osteodystrophy.
- Twenty-three children showed radiographic changes in their jawbones, including lamina durae alterations.
- Complete loss of lamina durae was associated with advanced renal osteodystrophy and elevated serum parathyroid hormone and alkaline phosphatase levels.
- Jawbone changes appeared with similar frequency to other skeletal abnormalities and were present even in preterminal renal insufficiency.
Conclusions:
- Radiographic changes in the jawbones are frequent in children with chronic renal failure and renal osteodystrophy.
- While not an initial symptom, jawbone alterations, particularly lamina durae changes, are valuable indicators of renal osteodystrophy.
- Jawbone radiography can aid in the early detection of renal insufficiency in children, appearing concurrently with other skeletal manifestations.