[Periimplant alterations under cyclosporin A drug treatment]

One titanium implant of the Brånemark system and one Al2O2 ceramic implant each were inserted in the lower jaws of 6 Beagle dogs to evaluate the alterations of the periimplant tissues under CsA therapy. During the 3-6 months of CsA substitution hyperplastic alterations were observed as soon as after the 3rd week. These anomalies were most pronounced around the titanium implants.