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Related Concept Videos

Minerals01:26

Minerals

Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
What is the Skeletal System?01:02

What is the Skeletal System?

Overview
Introduction to Electrolytes01:33

Introduction to Electrolytes

In humans, electrolytes play a vital role in various physiological processes. Balancing electrolyte levels is essential for normal body functions; their imbalance can be life-threatening. The major electrolytes include sodium, potassium, chloride, calcium, phosphate, and bicarbonate. They are primarily involved in physiological processes, such as nerve signal transmission, membrane trafficking, muscle contraction, buffering body fluids, and balancing water levels in the body.
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One...
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

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Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
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Skeletal fluorosis from instant tea.

Michael P Whyte1, William G Totty, Vivienne T Lim

  • 1Division of Bone and Mineral Diseases, Washington University School of Medicine at Barnes-Jewish Hospital, St Louis, Missouri, USA.

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
|January 9, 2008
PubMed
Summary
This summary is machine-generated.

Excessive consumption of extra-strength instant tea led to skeletal fluorosis (SF) in a woman due to high fluoride (F(-)) levels. This highlights the need for understanding safe fluoride limits in popular beverages.

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Area of Science:

  • Endocrinology
  • Toxicology
  • Orthopedics

Background:

  • Skeletal fluorosis (SF) is linked to prolonged intake of fluoride (F(-)) in well water (>4 ppm).
  • Teas, especially black and green varieties, can be significant sources of dietary F(-).
  • A case in 2005 highlighted SF from daily consumption of double-strength instant tea.

Observation:

  • A 49-year-old woman presented with chronic musculoskeletal pain and axial osteosclerosis.
  • She reported consuming 2 gallons of extra-strength instant tea daily since age 12.
  • Diagnostic tests revealed elevated serum and urinary F(-) levels, and high F(-) concentrations in nail clippings.

Findings:

  • Radiographs confirmed marked osteosclerosis of the axial skeleton without ligament calcification.
  • Dual-energy X-ray absorptiometry (DXA) showed significantly elevated bone mineral density (Z-scores +10.3 lumbar spine, +2.8 total hip).
  • The prepared instant tea contained 5.8 ppm F(-), with the tea powder contributing ~35 mg of daily F(-) intake.

Implications:

  • Habitual intake of large volumes of extra-strength instant tea can cause skeletal fluorosis (SF).
  • This case underscores the importance of recognizing potential skeletal safety limits for popular beverages.
  • Further research is needed to understand the long-term skeletal effects of modern tea preparations.