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06:06
Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
[Osteonecrosis of the knee]
1Istanbul Universitesi Cerrahpaşa Tip Fakültesi Ortopedi ve Travmatoloji Anabilim Dali, Istanbul, Turkey. karli@superonline.com
Acta Orthopaedica Et Traumatologica Turcica
|October 11, 2008
Summary
Osteonecrosis of the knee, a condition affecting knee bone health, presents as spontaneous or secondary types. Treatment options range from conservative management to surgical interventions like osteotomy and arthroplasty.
Area of Science:
- Orthopedic Surgery
- Bone Necrosis Research
- Knee Joint Pathologies
Context:
- Osteonecrosis of the knee (ONK) was initially described in 1968.
- ONK is categorized into spontaneous and secondary forms, differing in patient demographics and presentation.
- Etiology remains multifactorial, with associations to steroid therapy, alcoholism, and inflammatory conditions.
Purpose:
- To review the classification, etiology, and diverse treatment modalities for osteonecrosis of the knee.
- To provide an overview of current understanding and management strategies for ONK.
- To consolidate information on both spontaneous and secondary osteonecrosis of the knee.
Summary:
- Spontaneous osteonecrosis typically affects unilateral knees in individuals over 60.
- Secondary osteonecrosis presents in younger patients, often with bilateral and multifocal knee involvement.
- Treatment strategies encompass conservative measures, arthroscopic procedures, osteochondral transplantation, and joint replacement (arthroplasty).
Impact:
- Highlights the importance of differentiating between spontaneous and secondary ONK for tailored treatment.
- Underscores the need for further research into the unclear etiology of osteonecrosis of the knee.
- Provides a comprehensive summary of surgical and non-surgical interventions for ONK management.
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