Related Experiment Video
Updated: Jul 8, 2026

09:04
In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging
Published on: June 8, 2017
Overt bleeding in malarial patients: experience and review
1Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.com
Summary
Malaria, a growing global parasitic infection, frequently causes overt bleeding. Doctors in endemic areas should consider malaria in patients with unexplained fever and bleeding.
Area of Science:
- Tropical Medicine
- Infectious Diseases
- Parasitology
Background:
- Malaria is a significant global parasitic disease with increasing incidence.
- Bleeding is a notable clinical symptom associated with malaria.
- Understanding malarial bleeding presentations is crucial for patient management.
Purpose of the Study:
- To review the author's experience with overt bleeding in 50 Thai malaria patients.
- To synthesize existing literature on bleeding manifestations in malaria.
- To highlight the importance of recognizing malaria as a cause of bleeding.
Main Methods:
- Retrospective review of 50 malaria patients with overt bleeding.
- Literature review on malarial bleeding.
- Clinical case series analysis.
Main Results:
- Overt bleeding is a common clinical presentation in malaria patients.
- The study documented bleeding in 50 Thai patients in a rural hospital setting.
- Literature supports the occurrence of bleeding in malaria.
Conclusions:
- Overt bleeding is not an uncommon complication of malaria.
- General practitioners in malaria-endemic regions must consider malaria in patients with unexplained fever and bleeding.
- Early recognition and diagnosis of malaria are vital for managing bleeding complications.
Related Concept Videos
Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Esophageal Varices-II: Clinical Features and Management
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
