Related Experiment Video
Updated: Jul 8, 2026

Opsono-Adherence Assay to Evaluate Functional Antibodies in Vaccine Development Against Bacillus anthracis and Other Encapsulated Pathogens
Published on: May 19, 2020
[Adherence to immunization among children with special health care needs]
Yanahara Solís1, Lilian Bolte, Jennipher Johnson
1Departamento de Pediatría, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Insights
Children with special health care needs (CSHCN) often miss vaccinations, including the Expanded Program on Immunization (EPI). Hospitalizations present opportunities to improve CSHCN immunization rates and prevent infectious disease complications.
Area of Science:
- Pediatric Infectious Diseases
- Public Health and Epidemiology
- Childhood Chronic Illness Management
Context:
- The prevalence of children with special health care needs (CSHCN) is rising, increasing their vulnerability to infectious diseases.
- CSHCN often experience chronic illnesses, placing them at higher risk for severe complications from preventable infections.
Purpose:
- To evaluate adherence to the Expanded Program on Immunization (EPI) schedules in CSHCN.
- To assess the administration rates of other expert-recommended vaccines in this vulnerable population.
Summary:
- A retrospective analysis of 70 hospitalized CSHCN revealed significant delays in EPI vaccination schedules for 42.9% of participants.
- Common reasons for delays included prior hospitalizations and minor morbidity, with a notable percentage attributed to unjustified causes.
- While 70% of CSHCN received prescriptions for additional vaccines, only 25 actually received them, indicating poor uptake of recommended immunizations.
Impact:
- CSHCN demonstrate suboptimal adherence to routine and recommended vaccination protocols.
- Healthcare providers should leverage all patient encounters, including hospitalizations, to ensure timely and complete immunizations for CSHCN.
- Improving vaccination coverage in CSHCN is crucial for mitigating infectious disease risks and preventing severe health outcomes.
Unlabelled:
The proportion of children with special health care needs (CSHCN) due to chronic illness is increasing. They have a high risk of complications due to infectious diseases.
Objective:
To describe adherence to the Expanded Program of Immunization (EPI) and administration of other expert recommended vaccines in CSHCN.
Patients And Methods:
In a retrospective manner information on chronic disease, EPI vaccines administration, reasons for delays, prescription and administration of additionally recommended vaccines was registered in a cohort of hospitalized CSHCN.
Results:
Seventy children were analyzed. Thirty (42.9%) had at least one delay in EPI immunization schedule; 40% due to previous hospitalizations, 26.7% due to minor morbidity and 20% due to other unjustified reasons. Forty-nine (70.0%) received prescriptions for additional vaccines, but only 25 actually received them.
Conclusions:
CSHCN showed low adherence to EPI and received few additionally recommended vaccines. Every contact with these patients, including hospitalization should be used to update immunizations.
Related Concept Videos
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Vaccinations
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
Pharmacokinetics in Pediatric Patients: Drug Excretion
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
