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Updated: Jul 8, 2026

Comparative Analysis of Human Growth Hormone in Serum Using SPRi, Nano-SPRi and ELISA Assays
Published on: January 7, 2016
X-linked hypogammaglobulinemia and isolated growth hormone deficiency: an update
Donn M Stewart1, Lan Tian, Luigi D Notarangelo
1Immunophysiology Section, Metabolism Branch, CCR, NCI, National Institute of Health, Bldg. 10, Bethesda, MD 20892, USA.
Abstract:
X-linked hypogammaglobulinemia and isolated growth hormone deficiency (XLH-GHD, OMIM # 307200) is a primary immunodeficiency disorder characterized by pan-hypogammaglobulinemia and isolated growth hormone deficiency. The disease, which is only known to occur in a single family, shares many features with X-linked agammaglobulinemia (XLA, OMIM # 300300). The current review summarizes the clinical, laboratory, and genetic features of the disease as they have unfolded over the past quarter-century since its description.
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