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Detection of Cryptosporidium circulating antigens in human and calf sera
M A Gomez Morales1, E Pozio, G P Croppo
1Laboratory of Parasitology, Istituto Superiore di Sanità, Rome, Italy.
The Journal of Protozoology
|November 1, 1991
Abstract:
Cryptosporidium-specific circulating antigens were detected in sera of experimentally infected calves and AIDS patients by an enzyme-linked immunosorbent assay. Antigenemia was detectable from 2 to a minimum of 22 days post-infection (d.p.i.) in calves whose feces were parasitologically positive from 2-10 d.p.i. Antigenemia was detected in AIDS patients showing no a sero-conversion to immunoglobulin (Ig) M or to IgG. The detection of circulating antigens in humans allows early diagnosis of cryptosporidiosis, even in immunosuppressed patients.