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Related Concept Videos

Probiotics01:22

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Microbiota Modulation by Antibiotics01:21

Microbiota Modulation by Antibiotics

Antibiotics have revolutionized modern medicine by saving countless lives from bacterial infections. However, their widespread use has inadvertently harmed the delicate balance of the human gut microbiota. The gut microbiota, a complex community of bacteria, archaea, viruses, and fungi, plays a vital role in regulating metabolism, immune responses, and maintaining intestinal health. Antibiotics, especially broad-spectrum types, disrupt this ecosystem by eradicating both harmful and beneficial...
Dysbiosis of the Gut Microbiota01:18

Dysbiosis of the Gut Microbiota

The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...
Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity, and disease...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...

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Related Experiment Video

Updated: Jul 8, 2026

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

Clinical indications for probiotics: an overview.

B R Goldin1, S L Gorbach

  • 1Tufts University School of Medicine, Boston, Massachusetts 02111, USA. barry.goldin@tufts.edu

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|January 10, 2008
PubMed
Summary
This summary is machine-generated.

Probiotics offer proven benefits for various conditions like diarrhea and allergies, with potential future applications in cancer and diabetes. Lactobacillus rhamnosus GG and Saccharomyces boulardii show the most significant health advantages.

Related Experiment Videos

Last Updated: Jul 8, 2026

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
08:38

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

Area of Science:

  • Microbiology
  • Gastroenterology
  • Immunology

Background:

  • Probiotic bacteria are utilized for managing a wide spectrum of human ailments.
  • Emerging research suggests novel applications for probiotics in future medical interventions.

Purpose of the Study:

  • To review the established and potential therapeutic applications of probiotic bacteria.
  • To identify specific probiotic strains with documented efficacy.

Main Methods:

  • Review of randomized double-blind studies and research investigations.
  • Analysis of evidence for probiotic effectiveness across various health conditions.

Main Results:

  • Probiotics are effective in treating acute and antibiotic-induced diarrhea.
  • Evidence supports prevention of food allergies, traveler's diarrhea, C. difficile colitis, and UTIs.
  • Potential benefits for respiratory infections, dental caries, IBS, and IBD are indicated.
  • Future applications may include cancer, diabetes, and rheumatoid arthritis.
  • Lactobacillus rhamnosus GG and Saccharomyces boulardii demonstrate the most extensive benefits.

Conclusions:

  • Probiotics possess a broad range of current and potential health benefits.
  • Specific strains like L. rhamnosus GG and S. boulardii are key players in probiotic therapy.
  • Continued research is warranted for exploring novel probiotic applications.