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Expression of Exogenous Cytokine in Patient-derived Xenografts via Injection with a Cytokine-transduced Stromal Cell Line
Published on: May 10, 2017
Post-transplant T-cell type lymphoproliferative disorder.
Zubair Ahmad1, Aamir Ahsan, Usman Sheikh
1Department of Pathology and Microbiology, Aga Khan University, Hospital, Stadium Road, Karachi.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|January 10, 2008
Summary
Post-Transplant Lymphoproliferative Disorder (PTLD) is a rare lymphoma after organ transplant, often linked to Ebstein-Barr Virus (EBV). This report details a unique case of T-cell PTLD in a kidney transplant recipient.
Area of Science:
- Immunology
- Oncology
- Transplantation Medicine
Background:
- Post-Transplant Lymphoproliferative Disorder (PTLD) is a serious complication following solid organ or bone marrow transplantation.
- It arises from immunosuppression, with most cases linked to Ebstein-Barr Virus (EBV) infection.
- PTLD predominantly presents as B-cell lymphoma, with T-cell PTLD being less common.
Purpose of the Study:
- To report a rare case of T-cell PTLD.
- To highlight the occurrence of T-cell PTLD in a renal transplant recipient.
Main Methods:
- Case report presentation.
- Review of clinical data and diagnostic findings for a renal transplant recipient diagnosed with PTLD.
Main Results:
- The patient, a renal transplant recipient, developed PTLD.
- The PTLD in this case was identified as the less common T-cell type.
Conclusions:
- T-cell PTLD can occur in renal transplant recipients.
- This case underscores the importance of considering diverse PTLD subtypes in post-transplant patients.
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