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Updated: Jul 8, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Idiopathic short stature: definition, epidemiology, and diagnostic evaluation
J M Wit1, P E Clayton, A D Rogol
1Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands. j.m.wit@lumc.nl
Abstract:
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present. It can be subcategorized into familial and non-familial ISS, and according to pubertal delay. It should be differentiated from dysmorphic syndromes, skeletal dysplasias, short stature secondary to a small birth size (small for gestational age, SGA), and systemic and endocrine diseases. ISS is the diagnostic group that remains after excluding known conditions in short children.
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