Related Experiment Video
Updated: Jun 11, 2026

Isolation and Transplantation of Different Aged Murine Thymic Grafts.
Published on: May 13, 2015
[Application and curative effect of plasma exchange in myasthenia gravis patients with thymectomy]
Ya-mei Shen1, Wei Gong, Jian-xin Liu
1Department of Blood Transfusion, Xiangya Hospital, Central South University, Changsha 410008, China. meizi7436@yahoo.com.cn
Objective:
To explore the application of plasma exchange in myasthenia gravis (MG) patients with thymectomy, and to evaluate its curative effects.
Methods:
The clinical data of 50 patients with thymectomy were analyzed retrospectively, and the patients were divided into Group A (23 cases, undergoing thymectomy and plasma exchange) and Group B (27 cases, undergoing thymectomy). The difference of serum concentration of AChRab was examined by ELISA, and the time of auxiliary breath, crisis of myasthenia and clinical evaluation in the 2 groups were compared.
Results:
Serum concentration of AChRab in Group A descended obviously after the plasma exchange. One day and one week after the operation, the AChRab concentration in Group A was obviously lower than that in Group B, but there was no difference one month after the operation. One week after the operation, the time of auxiliary breath,crisis of myasthenia and clinical evaluation in Group A were less than those in Group B.
Conclusion:
Plasma exchange together with thymectomy can improve the temporary curative effects in patients with MG. It is safe and effective for MG.
More Related Videos
08:13Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice
Published on: April 10, 2019
07:39Renal Subcapsular Transplantation of 2'-Deoxyguanosine-Treated Murine Embryonic Thymus in Nude Mice
Published on: July 19, 2019
Related Concept Videos
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Myocarditis III: Medical Management
Electroconvulsive Therapy
Graves Disease II: Pathophysiology
Myasthenia Gravis ll: Pathophysiology