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Updated: Aug 5, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Published on: March 15, 2019
[Prevention of heart failure by adapting the body to high-altitude hypoxia]
Abstract:
The impact of adaptation of the body to various high-altitude levels was thoroughly studied in 355 Chinchilla rabbits. It was found that adaptation of the body to high-altitude conditions prevents to a great measure a complex of phenomena specific to heart failure: disturbed myocardial RNA metabolism, reduced cardiac volume, increased mass of circulating blood, destructive myocardial changes, etc. Adaptation to high-altitude hypoxia is conducive to resistance of the heart to additional load and may be used in the prevention of heart failure as well as in the prevention of heart diseases and circulatory disorders.
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