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[The effect of potential antineoplastic antibiotics and the metal complex compound cisplatin on in vitro
1Institut für Mikrobiologie und Experimentelle Therapie (IMET) Jena.
Die Pharmazie
|December 1, 1991
Abstract:
Under standardized conditions the influence of the drugs lambdamycin, violamycin, granatomycin C, daunorubicin and cisplatin on the phagocytosis has been tested. Therapeutical doses of lambdamycin, daunorubicin and cisplatin did not have any obvious impairment on the phagocytosis. Contrarily to this granatomycin C (an isochromanchinon antibiotic) and violamycin (an anthracyclin in high concentrations) significantly depressed the phagocytosis of PMN.