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Updated: Jul 8, 2026

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
Published on: June 20, 2017
Biomechanical risk estimates for mild traumatic brain injury
J R Funk1, S M Duma, S J Manoogian
1Biodynamic Research Corporation, San Antonio, Texas, USA.
Collegiate football players sustain more severe head impacts than previously believed without injury. This study proposes new reference values for assessing mild traumatic brain injury (MTBI) risk from head impacts.
Area of Science:
- Biomechanics
- Neuroscience
- Sports Medicine
Background:
- Mild traumatic brain injury (MTBI) is a significant concern in contact sports.
- Previous research has limited data on head impact tolerance in living humans.
Purpose of the Study:
- To characterize the risk of MTBI in collegiate American football players.
- To establish preliminary injury assessment reference values for head impacts.
Main Methods:
- Real-time head acceleration data collected from helmet-mounted accelerometers.
- Analysis of over 27,000 head impacts, including those resulting in MTBI.
- Development of parametric risk curves by normalizing injury incidence with impact exposure.
Main Results:
- Four instances of MTBI were recorded from over 27,000 head impacts.
- Living humans can tolerate higher head impact forces than previously assumed.
- Proposed 10% MTBI risk values: 165 g peak linear acceleration, 400 HIC, 9000 rad/s² peak angular acceleration.
Conclusions:
- Collegiate football players experience substantial head impacts without apparent injury.
- The findings suggest current injury thresholds may be conservative.
- New reference values are proposed for MTBI risk assessment in head impacts.
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