[Primary clear cell sarcoma of the ileum]
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Updated: Jul 8, 2026

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Nathalie Marcon1, Karine Montagne, Sébastien Corby
1Service d'anatomie et cytologie pathologiques, Hôpitaux de Brabois, CHU de Nancy, 5 allée du Morvan, 54511 Vandoeuvre-les-Nancy.
Abstract:
Clear cell sarcoma or malignant melanoma of soft tissue is a high-grade sarcoma with melanocytic differentiation, essentially involving tendons and aponeuroses of distal extremities in young adults. Visceral locations are exceptional and only 8 cases involving the gastrointestinal tract are reported in the literature. We present a case of an ileal clear cell sarcoma discovered in a 26-year-old woman. Moreover, we emphasize on the diagnosis difficulties of this rare type of sarcoma, characterized by the specific translocation t(12;22)(q13;q12).
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