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Related Concept Videos

Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Related Experiment Video

Updated: Jul 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

[Malignant proliferating trichilemmal tumor].

Maha Driss1, Dhouha Bacha, Karima Mrad

  • 1Service d'anatomie et cytologie pathologiques, Institut Salah Azaiez, 1006 Bab Saadoun, Tunis (Tunisie). maha.driss@rns.tn

Annales De Pathologie
|January 11, 2008
PubMed
Summary

Proliferating trichilemmal tumors (PTT) are rare scalp lesions. This report details a malignant PTT in a 44-year-old man, discussing diagnostic criteria for benign versus malignant PTT.

Related Experiment Videos

Last Updated: Jul 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

  • Dermatopathology
  • Oncology

Background:

  • Proliferating trichilemmal tumor (PTT) is a rare skin neoplasm.
  • PTT typically affects elderly women, predominantly on the scalp.
  • Malignant transformation of PTT is infrequently reported, with approximately 40 cases documented.

Observation:

  • This study presents a case of malignant PTT occurring on the scalp.
  • The patient was a 44-year-old man, an atypical demographic for this condition.
  • Clinical presentation and histopathological findings were meticulously documented.

Findings:

  • The case highlights a malignant PTT in a younger male patient.
  • Discussion focuses on distinguishing features between benign and malignant PTT.
  • Histological criteria are crucial for accurate diagnosis and prognosis.

Implications:

  • This case expands the known demographic profile for malignant PTT.
  • Understanding diagnostic criteria is vital for appropriate clinical management.
  • Further research may elucidate factors contributing to PTT malignancy.