Related Experiment Video
Updated: Jul 8, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Temperature-induced excess mortality in Moscow, Russia
Boris Revich1, Dmitri Shaposhnikov
1Environmental Health Laboratory, Institute of Forecasting, Russian Academy of Sciences, Moscow, Russia. revich@ecfor.ru
Extreme temperatures in Moscow significantly increase mortality, especially for those aged 75+. Both heat and cold exacerbate deaths from cardiovascular and respiratory diseases, highlighting the need for public health interventions.
Area of Science:
- Environmental Health
- Epidemiology
- Biometeorology
Background:
- Long-term temperature trends in Moscow show significant variations.
- Understanding the impact of temperature on acute mortality is crucial for public health.
- Identifying vulnerable populations is essential for targeted interventions.
Purpose of the Study:
- To evaluate the relationship between daily temperature fluctuations and acute mortality in Moscow.
- To identify specific population groups (by age and cause of death) vulnerable to temperature changes.
- To quantify the mortality risks associated with both increases and decreases in temperature.
Main Methods:
- Analysis of long-term temperature data and acute mortality records in Moscow.
- Statistical modeling to assess the V-shaped mortality-temperature relationship.
- Lag analysis to determine the time frame of mortality response to temperature changes.
Main Results:
- A V-shaped mortality-temperature relationship was observed, with a minimum mortality point around 18°C.
- Increases in temperature above 18°C led to higher mortality from non-accidental causes, coronary heart disease, cerebrovascular diseases, and respiratory diseases.
- Decreases in temperature from 18°C to -10°C also significantly increased mortality across all studied causes.
- Mortality risks were substantially higher (13-30%) for individuals aged 75 years and older.
- Increased daily temperature variation also correlated with higher non-accidental mortality.
Conclusions:
- Both extreme heat and cold pose significant risks to public health in Moscow, impacting cardiovascular and respiratory systems.
- Older adults (75+ years) are a particularly vulnerable demographic requiring focused protection strategies.
- Daily temperature variability is an independent risk factor for mortality, necessitating consideration in climate adaptation planning.
Related Concept Videos
Increased Body Temperature
Factors Affecting Body Temperature
Factors may include:
Homeostatic Imbalances in Body Temperature
Decreased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Requirements for Human Life
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
