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Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
Risk factors for pressure ulcer development in a best practice surgical intensive care unit
Heidi Frankel1, Jason Sperry, Lewis Kaplan
1Division of Burn/Trauma/Critical Care, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, USA. heidi.frankel@utsouthwestern.edu
Insights
Pressure ulcers (PU) affect 3% of surgical intensive care unit patients. Key risk factors include diabetes, spinal cord injury, age over 60, and high creatinine levels.
Area of Science:
- Critical Care Medicine
- Surgical Nursing
- Patient Safety
Background:
- Pressure ulcers (PU) are a significant concern in surgical intensive care units (ICUs).
- Standard preventative measures like specialized beds and early nutrition are often implemented.
Purpose of the Study:
- To determine the incidence of pressure ulcers in a surgical ICU.
- To identify independent risk factors for PU development in this patient population.
Main Methods:
- A 12-month prospective data collection of patients admitted to a university hospital surgical ICU.
- Statistical analysis including Chi-squared, t-tests, and logistic regression.
- Identification of PU patients based on new stage II or greater lesions during or after ICU stay.
Main Results:
- The incidence of PU was 3% (25/820 patients).
- Independent predictors for PU included diabetes (OR 2.7), spinal cord injury (OR 16.8), age > 60 years (OR 2.9), and creatinine > 3 mg/dL (OR 3.7).
- No significant differences were found in age, APACHE score, or gender between patients with and without PU.
Conclusions:
- Despite current preventative strategies, PU remains a challenge in surgical ICUs.
- Diabetes, spinal cord injury, advanced age, and renal insufficiency are critical independent risk factors.
- Consideration of additional interventions like early mobilization may be beneficial.
Abstract:
We describe the incidence of and define risk factors for pressure ulcers (PU) in the surgical intensive care unit (ICU). Twelve months of data were collected on all patients admitted to the intensivist-run surgical ICU of a university hospital. PU patients were those who developed a new stage II or greater lesion during or after a surgical ICU stay as identified in Project Impact, ICD9 discharge, or ICU complications databases. Patients were nursed in pressure-relieving beds with nutrition initiated by 72 hours. Chi2, t test, and logistic regression statistics were used. Three percent (25/820) developed PU. Age, ICU length of stay, Acute Physiology and Chronic Health Evaluation Score (APACHE), and gender were not different between those with and without PU. Patients with PU had a higher blood urea nitrogen/creatinine (30.5/2.2 mg/dL vs 22.0/1.6 mg/dL) and were more frequently vascular patients (28 vs 14.1%), diabetics (40 vs 17.2%), paraplegics (8 vs 0.2%) (all P < 0.01), and patients on pressors (28.0 vs 11.8%, P < 0.02). Multivariate analysis revealed that diabetes (odds ratio [OR] 2.7, 95%, confidence interval [CI] 1.1-6.4), spinal cord injury (OR 16.8, 95%, CI 1.5-183), age > 60 years (OR 2.9, 95%, CI 1.2-7.1), and a creatinine >3 mg/dL (OR 3.7, 95%, CI 1.2-9.3) were independent predictors of PU. Despite universal use of specialty beds and early nutrition, pressure ulcers developed in 3 per cent. Independent risk factors include age greater than 60 years, diabetes, spinal cord injury, and renal insufficiency. Additional modalities, such as aggressive early mobilization, might be warranted in this cohort.
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