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Updated: Aug 12, 2026

06:19
The Mouse Forced Swim Test
Published on: January 29, 2012
Effects of cholinomimetics and cholinolytics in a despair test in mice
1Department of Pharmacology, Silesian Medical Academy, Medical Faculty in Zabrze, Poland.
Abstract:
Cholinomimetics prolonged, while cholinolytics shortened the immobility time ("despair reaction") in a forced swimming test. It is concluded that this behavioral test is useful in studies on the central cholinergic system in mice.
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