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Endocarditis I: Introduction

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...

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Updated: Jul 8, 2026

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface

Published on: July 21, 2016

Infective endocarditis during pregnancy: case report.

B Nyawo¹, R F Shoaib, K Evemy

¹Departments of Cardiothoracic Surgery, Newcastle upon Tyne, UK.

The Heart Surgery Forum

|January 12, 2008

Summary

This summary is machine-generated.

Infective endocarditis in pregnancy necessitates urgent intervention. A 31-week pregnant patient underwent cesarean delivery and valve surgery, resulting in a positive outcome for both mother and child.

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Last Updated: Jul 8, 2026

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface

Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface

Published on: July 21, 2016

Area of Science:

Cardiology
Obstetrics
Infectious Diseases

Background:

Infective endocarditis (IE) during pregnancy poses significant risks to both mother and fetus.
Management requires a multidisciplinary approach, balancing maternal health with fetal well-being.

Observation:

A 29-year-old woman at 31 weeks gestation presented with severe IE.
Echocardiography revealed aortic valve vegetations and severe mitral regurgitation.
Blood cultures confirmed Streptococcus sanguis infection.

Findings:

The patient experienced impending hemodynamic collapse, necessitating emergent cesarean delivery.
Following delivery, aortic valve replacement and mitral valve repair using bovine pericardium were performed.
The mother and neonate demonstrated a favorable recovery at the 10-month follow-up.

Implications:

This case highlights the successful management of IE in advanced gestation.
It underscores the importance of timely surgical intervention and multidisciplinary care in pregnant patients with IE.
The favorable outcome suggests that aggressive management can lead to good results for both mother and child.