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Published on: June 8, 2022
Successful aortic valve replacement using dilutional ultrafiltration during cardiopulmonary bypass in a patient with
Kenji Iino1, Shigeyuki Tomita, Shohjiro Yamaguchi
1Department of General and Cardiothoracic Surgery, Kanazawa University School of Medicine, 13-1 Takaramachi, Kanazawa 920-8641, Japan. k-iino@m8.dion.ne.jp
Insights
Open-heart surgery poses risks for patients with severe cirrhosis. Dilutional ultrafiltration during cardiopulmonary bypass improved outcomes for a patient with Child-Pugh class C cirrhosis undergoing aortic valve replacement.
Area of Science:
- Cardiology
- Hepatology
- Surgical Innovation
Background:
- Open-heart surgery in Child-Pugh class C cirrhosis patients carries high risks, including major postoperative complications and extended hospital stays.
- Aortic valve stenosis can lead to severe heart failure, necessitating surgical intervention even in high-risk patient populations.
Observation:
- A case report details a patient with Child-Pugh class C cirrhosis and severe aortic valve stenosis who required open-heart surgery.
- The patient underwent successful aortic valve replacement utilizing cardiopulmonary bypass (CPB).
Findings:
- Dilutional ultrafiltration (DUF) was employed during CPB to mitigate adverse effects.
- The patient experienced a smooth recovery without significant postoperative complications.
Implications:
- DUF during CPB may offer a beneficial strategy for improving surgical outcomes in patients with decompensated cirrhosis undergoing cardiac procedures.
- This approach could enhance patient recovery and reduce complications in a vulnerable surgical cohort.
Abstract:
Open-heart surgery is a relatively high-risk procedure when performed in patients with Child-Pugh class C cirrhosis. Even though they can tolerate cardiac surgery with cardiopulmonary bypass (CPB), most of them suffer major postoperative complications and prolonged hospital stay. The present report describes a case of a patient with Child-Pugh class C cirrhosis who developed severe heart failure secondary to aortic valve stenosis. The patient underwent successful aortic valve replacement with the use of dilutional ultrafiltration during CPB to reduce adverse effects of CPB. He recovered smoothly after the operation without major postoperative complications. Thus, the use of dilutional ultrafiltration (DUF) during CPB appears to produce beneficial effects for improving outcomes in patients with decompensated cirrhosis who require open-heart surgery.

