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Solitary rectal ulcer syndrome in children

Alireza S Keshtgar1

  • 1University Hospital Lewisham, National Health Service Trust, London, UK. ali.keshtgar@uhl.nhs.uk

European Journal of Gastroenterology & Hepatology
|January 12, 2008
PubMed

Insights

Solitary rectal ulcer syndrome (SRUS) in children causes rectal bleeding and pain. Treatment includes conservative measures, but surgery or botulinum toxin may be needed for severe cases.

Area of Science:

  • Pediatric Gastroenterology
  • Colorectal Surgery

Background:

  • Solitary rectal ulcer syndrome (SRUS) is a rare pediatric condition.
  • Symptoms include rectal bleeding, mucus passage, straining, tenesmus, pain, and rectal prolapse.
  • Etiology is unclear, likely involving rectal ischemia and pelvic floor dysfunction.

Purpose of the Study:

  • To review the presentation, etiology, and management of SRUS in children.
  • To explore potential therapeutic roles for interventions like botulinum toxin injection.

Main Methods:

  • Review of clinical presentation and diagnostic findings.
  • Analysis of treatment outcomes for conservative and surgical interventions.
  • Exploration of the pathophysiology involving paradoxical muscle contractions.

Main Results:

  • Conservative treatments (diet, laxatives, biofeedback) are often effective for constipation.
  • Refractory cases may require rectal ulcer excision or surgery for prolapse.
  • Botulinum toxin injection is a potential treatment for associated muscle dysfunction.

Conclusions:

  • SRUS management requires a multi-faceted approach.
  • Conservative measures are first-line treatments.
  • Further research into novel therapies like botulinum toxin is warranted for pediatric SRUS.

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