Related Experiment Video
Updated: Feb 19, 2026
08:27
Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
243
[Intraprostatic injection of azactam for chronic prostatitis]
1Second Affiliated Hospital of Guangzhou Medical College.
Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|November 1, 1991
Summary
Direct intraprostatic antibiotic injection using azactam effectively treated chronic prostatitis. This method achieved a high cure rate of 97.3% in 75 patients, offering a promising therapeutic option.
Area of Science:
- Urology
- Pharmacology
Context:
- Chronic prostatitis presents a significant clinical challenge.
- Conventional treatments may have limitations in achieving high drug concentrations within the prostate.
Purpose:
- To evaluate the efficacy and pharmacokinetic advantages of direct intraprostatic azactam injection for chronic prostatitis.
Summary:
- Seventy-five patients with chronic prostatitis received intraprostatic azactam via a transperineal route.
- This direct antibiotic injection achieved high prostate drug concentrations and prolonged effects, bypassing the lipoprotein epithelial membrane.
- A remarkable 97.3% cure rate was observed in the treated patients.
Impact:
- Demonstrates a highly effective treatment strategy for chronic prostatitis.
- Highlights the potential of targeted intraprostatic drug delivery for urological infections.
- Provides evidence for the favorable pharmacological profile of azactam in this application.
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