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Published on: March 30, 2018
T/NK cell lymphoma presenting as a "blocked nose"
Naomi Ketharanathan1, Peter Jan van Kipshagen, Wies Vasmel
1Department of Head and Neck Surgery, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, Amsterdam, The Netherlands. n.ketharanathan@gmail.com
A rare nasal T/NK cell lymphoma case highlights the need for early diagnosis. Treatment involved chemotherapy (cyclophosphamide, doxorubicin, vincristine, prednisone) and radiotherapy for this aggressive malignancy.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Nasal T/NK cell lymphoma is a rare and aggressive malignancy.
- Early diagnosis is crucial for improving patient outcomes.
Observation:
- A 63-year-old male presented with persistent rhinitis, sinusitis, and complete left nasal blockage.
- Histopathological investigation confirmed stage IE nasal T/NK cell lymphoma.
Findings:
- The patient received cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy.
- Involved-field radiotherapy was administered as part of the treatment regimen.
Implications:
- This case underscores the importance of a high clinical suspicion for prompt diagnosis.
- Combined locoregional radiotherapy and chemotherapy are the standard treatment, tailored to disease stage.
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