Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intraocular pressure and associated factors in children: the Shandong children eye study.

Investigative ophthalmology & visual science·2014

Same author

Novel compound heterozygous mutations identified in ADAMTSL4 gene in a Chinese family with isolated ectopia lentis.

Acta ophthalmologica·2014

Same author

Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Lancet (London, England)·2014

Same author

Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Lancet (London, England)·2014

Same author

Diabetic retinopathy and estimated cerebrospinal fluid pressure. The Beijing Eye Study 2011.

PloS one·2014

Same author

Ophthalmology: potential future developments in China and worldwide.

Chinese medical journal·2014

Search research articles

Related Experiment Video

Updated: Jul 8, 2026

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Ophthalmodynamometry and ischemic ophthalmopathy.

Jost B Jonas¹, Feras Kaltakji

¹Department of Ophthalmology, Mannheim of the Ruprecht-Karls-University Heidelberg, Heidelberg, Germany. Jost.Jonas@augen.ma.uni-heidelberg.de

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie

|January 15, 2008

Summary

A modified ophthalmodynamometer effectively detected ischemic ophthalmopathy by measuring significantly lower diastolic central retinal artery pressure in an affected eye. This tool aids in assessing ocular and cerebroafferent vessels in patients with symptomatic ocular ischemia.

More Related Videos

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Related Experiment Videos

Last Updated: Jul 8, 2026

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Area of Science:

Ophthalmology
Vascular Medicine
Medical Instrumentation

Background:

Investigating the clinical utility of a modified ophthalmodynamometer for diagnosing ischemic ophthalmopathy.
Highlighting the importance of early detection in managing vision-threatening conditions.

Observation:

A 70-year-old patient presented with unilateral vision loss, thin retinal arteries, intraretinal hemorrhages, and iris neovascularization.
A modified ophthalmodynamometer, incorporating a pressure sensor, was utilized for measurement.

Findings:

Ophthalmodynamometry revealed significantly lower diastolic central retinal artery pressure in the affected eye compared to the contralateral eye (14.6+/-2.2 vs. 45.5+/-5.1 arbitrary units).
Measurements from both eyes were significantly lower than those in a control group (73.8+/-6.2 arbitrary units) of 149 normal individuals.
Doppler sonography confirmed significant stenosis of the internal carotid artery, supporting the diagnosis of unilateral ischemic ophthalmopathy.

Implications:

Ophthalmodynamometry serves as a valuable supplementary diagnostic tool for evaluating oculo-afferent and cerebroafferent vessels.
This technique can aid clinicians in identifying and managing patients with symptomatic ocular ischemia.
Accurate assessment of retinal artery pressure is crucial for understanding the severity of cerebrovascular compromise affecting the eye.